The selling point for me was the highly accessible wipe compartment. Who needs to fuss around with getting wipes out of bag pockets or fighting with a wipe to come out of a loose wipe pouch!?! No parent on the go has time for that. The flap opens down and makes wipes super accessible. It also conceals the wipe pouch, so you don't look like you're carrying a diaper bag (if that matters to you.) The flap has a couple of compartments where you can hold a sanitary pad and tampon or two, if you need, but it can't hold much if you want the flap to close properly.The versatility of this bag is wonderful. I use this as a travel potty bag for my young children. It is discreet while managing to fit a change of clothes, a few pull-up pants, flushable wipes, sanitary potty seat liners/covers, and even a foldable travel potty seat. With the shoulder strap, it can be hung on a bathroom stall hook, and the flushable wipes can be accessed easily by the kids.*Note: The "insulated" bottle compartment is really a thin loop-sleeve, open on the top and bottom. While I have never used it for the intended purpose, I personally would not recommend relying on it for anything more than short term hot/cold insulation. i keep hand sanitizer or hand soap there.